wolf pack therapeutic approach
Concept: A group (2 to 3) of ADCs simultaneously intravenously injected can travel together seeking out the targeted tumor cells. Wolfpacks hunts by co-operation and have one of the highest success rates of all predators. Similarly, the group of antibodies bind to distinct areas of the target receptor and co-operate to induce receptor cross-linking which, improves the delivery of the drug inside tumor cells. This provides a more powerful knock-out punch to tumors.